James R. Howe Department of Surgery University of Iowa Carver College of Medicine Biography Publications Institution JoVE Articles James R. Howe has not added a biography. If you are James R. Howe and would like to personalize this page please email our Author Liaison for assistance. Publications Evaluation and Management of Neuroendocrine Tumors of the Pancreas The Surgical Clinics of North America. Aug, 2019 | Pubmed ID: 31255207 The Pancreas As a Site of Metastasis or Second Primary in Patients with Small Bowel Neuroendocrine Tumors Annals of Surgical Oncology. Aug, 2019 | Pubmed ID: 31011904 Effective Cytoreduction Can Be Achieved in Patients with Numerous Neuroendocrine Tumor Liver Metastases (NETLMs) Surgery. 01, 2019 | Pubmed ID: 30343949 Management of Small Bowel Neuroendocrine Tumors Journal of Oncology Practice. 08, 2018 | Pubmed ID: 30096273 The Distal Predilection of Small Bowel Neuroendocrine Tumors Annals of Surgical Oncology. Oct, 2018 | Pubmed ID: 30054825 Changes in Gene Expression in Small Bowel Neuroendocrine Tumors Associated with Progression to Metastases Surgery. 01, 2018 | Pubmed ID: 29154080 Is Multifocality an Indicator of Aggressive Behavior in Small Bowel Neuroendocrine Tumors? Pancreas. 10, 2017 | Pubmed ID: 28902780 The Surgical Management of Small Bowel Neuroendocrine Tumors: Consensus Guidelines of the North American Neuroendocrine Tumor Society Pancreas. 07, 2017 | Pubmed ID: 28609357 The North American Neuroendocrine Tumor Society Consensus Guidelines for Surveillance and Medical Management of Midgut Neuroendocrine Tumors Pancreas. 07, 2017 | Pubmed ID: 28609356 Increased Grade in Neuroendocrine Tumor Metastases Negatively Impacts Survival Annals of Surgical Oncology. Aug, 2017 | Pubmed ID: 28560597 Localization of Unknown Primary Site with Ga-DOTATOC PET/CT in Patients with Metastatic Neuroendocrine Tumor Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 07, 2017 | Pubmed ID: 28153957 Identification of Primary Tumors in Patients Presenting with Metastatic Gastroenteropancreatic Neuroendocrine Tumors Surgery. 01, 2017 | Pubmed ID: 27863780 Translational Diagnostics and Therapeutics in Pancreatic Neuroendocrine Tumors Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2016 | Pubmed ID: 27742788 Serous Cystadenocarcinoma of the Pancreas: Clinical Features and Management of a Rare Tumor Digestive Surgery. 2016 | Pubmed ID: 26998825 Biochemical Diagnosis and Preoperative Imaging of Gastroenteropancreatic Neuroendocrine Tumors Surgical Oncology Clinics of North America. Jan, 2016 | Pubmed ID: 26610781 Liver-directed Surgery of Neuroendocrine Metastases: What is the Optimal Strategy? Surgery. Jan, 2016 | Pubmed ID: 26454679 Somatic Alterations of CDKN1B Are Associated with Small Bowel Neuroendocrine Tumors Cancer Genetics. Sep, 2015 | Pubmed ID: 26603463 Imaging in Neuroendocrine Tumors: an Update for the Clinician International Journal of Endocrine Oncology. 2015 | Pubmed ID: 26257863 The Supporting Role of (18)FDG-PET in Patients with Neuroendocrine Tumors Annals of Surgical Oncology. Jul, 2015 | Pubmed ID: 25777088 Esophageal Cancer in a Family with Hamartomatous Tumors and Germline PTEN Frameshift and SMAD7 Missense Mutations Cancer Genetics. Jan-Feb, 2015 | Pubmed ID: 25554686 A Practical Method to Determine the Site of Unknown Primary in Metastatic Neuroendocrine Tumors Surgery. Dec, 2014 | Pubmed ID: 25456909 Gene Expression Accurately Distinguishes Liver Metastases of Small Bowel and Pancreas Neuroendocrine Tumors Clinical & Experimental Metastasis. Dec, 2014 | Pubmed ID: 25241033 Limitations of Somatostatin Scintigraphy in Primary Small Bowel Neuroendocrine Tumors The Journal of Surgical Research. Aug, 2014 | Pubmed ID: 24950794 Medical Management of Metastatic Medullary Thyroid Cancer Cancer. Nov, 2014 | Pubmed ID: 24942936 Pancreastatin Predicts Survival in Neuroendocrine Tumors Annals of Surgical Oncology. Sep, 2014 | Pubmed ID: 24752611 GIPR Expression in Gastric and Duodenal Neuroendocrine Tumors The Journal of Surgical Research. Aug, 2014 | Pubmed ID: 24565507 Gastric Inhibitory Polypeptide Receptor (GIPR) is a Promising Target for Imaging and Therapy in Neuroendocrine Tumors Surgery. Dec, 2013 | Pubmed ID: 24238043 Overexpression of Membrane Proteins in Primary and Metastatic Gastrointestinal Neuroendocrine Tumors Annals of Surgical Oncology. Dec, 2013 | Pubmed ID: 24114056 Translational Research in Endocrine Surgery Surgical Oncology Clinics of North America. Oct, 2013 | Pubmed ID: 24012403 Discriminating Pheochromocytomas from Other Adrenal Lesions: the Dilemma of Elevated Catecholamines Annals of Surgical Oncology. Nov, 2013 | Pubmed ID: 23884753 Neuroendocrine Tumors Arising in Meckel's Diverticula: Frequency of Advanced Disease Warrants Aggressive Management Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract. Jun, 2013 | Pubmed ID: 23558715 BMPR1A Mutations in Juvenile Polyposis Affect Cellular Localization The Journal of Surgical Research. Oct, 2013 | Pubmed ID: 23433720 Invasion in Follicular Thyroid Cancer Cell Lines is Mediated by EphA2 and PAkt Surgery. Dec, 2012 | Pubmed ID: 23158188 Differentiation of Small Bowel and Pancreatic Neuroendocrine Tumors by Gene-expression Profiling Surgery. Dec, 2012 | Pubmed ID: 23158174 Germline Mutations in SMAD4 Disrupt Bone Morphogenetic Protein Signaling The Journal of Surgical Research. May, 2012 | Pubmed ID: 22316667 SP1 Regulates the Transcription of BMPR1A The Journal of Surgical Research. Nov, 2011 | Pubmed ID: 21872883 Surveillance and Intervention After Thyroid Lobectomy Annals of Surgical Oncology. Jun, 2011 | Pubmed ID: 21246403 Altered Expression of Iron Regulatory Genes in Cirrhotic Human Livers: Clues to the Cause of Hemosiderosis? Laboratory Investigation; a Journal of Technical Methods and Pathology. Dec, 2008 | Pubmed ID: 18838961 A Family with Two Consecutive Nonsense Mutations in BMPR1A Causing Juvenile Polyposis Cancer Genetics and Cytogenetics. Feb, 2008 | Pubmed ID: 18262054 Minimally Invasive Parathyroidectomy and Preoperative MIBI Scans: Correlation of Gland Weight and Preoperative PTH Journal of the American College of Surgeons. Oct, 2007 | Pubmed ID: 17916517 The Prevalence of MADH4 and BMPR1A Mutations in Juvenile Polyposis and Absence of BMPR2, BMPR1B, and ACVR1 Mutations Journal of Medical Genetics. Jul, 2004 | Pubmed ID: 15235019 Common Deletion of SMAD4 in Juvenile Polyposis is a Mutational Hotspot American Journal of Human Genetics. May, 2002 | Pubmed ID: 11920286 Establishment and Characterization of Small Bowel Neuroendocrine Tumor Spheroids Po Hien Ear1, Guiying Li1, Meng Wu2, Ellen Abusada3, Andrew M. Bellizzi3, James R. Howe1 1Department of Surgery, University of Iowa Carver College of Medicine, 2High Throughput Screening Facility, University of Iowa Carver College of Medicine, 3Department of Pathology, University of Iowa Carver College of Medicine JoVE 60303 Cancer Research
Establishment and Characterization of Small Bowel Neuroendocrine Tumor Spheroids Po Hien Ear1, Guiying Li1, Meng Wu2, Ellen Abusada3, Andrew M. Bellizzi3, James R. Howe1 1Department of Surgery, University of Iowa Carver College of Medicine, 2High Throughput Screening Facility, University of Iowa Carver College of Medicine, 3Department of Pathology, University of Iowa Carver College of Medicine JoVE 60303 Cancer Research