Kay M. Brummond Department of Chemistry University of Pittsburgh Biography Publications Institution JoVE Articles Kay M. Brummond has not added a biography. If you are Kay M. Brummond and would like to personalize this page please email our Author Liaison for assistance. Publications Enantioselective Synthesis of 5,7-Bicyclic Ring Systems from Axially Chiral Allenes Using a Rh(I)-Catalyzed Cyclocarbonylation Reaction The Journal of Organic Chemistry. Mar, 2013 | Pubmed ID: 23485149 Synthesis and in Silico Screening of a Library of β-carboline-containing Compounds Beilstein Journal of Organic Chemistry. 2012 | Pubmed ID: 23019432 A Thermal Dehydrogenative Diels-Alder Reaction of Styrenes for the Concise Synthesis of Functionalized Naphthalenes Organic Letters. Sep, 2012 | Pubmed ID: 22913473 Synthesis and Photophysical Properties of a Series of Cyclopenta[b]naphthalene Solvatochromic Fluorophores Journal of the American Chemical Society. Aug, 2012 | Pubmed ID: 22793873 An Allenic Pauson-Khand Approach to 6,12-guaianolides Organic Letters. Dec, 2011 | Pubmed ID: 22070869 Complete Transfer of Chirality in an Intramolecular, Thermal [2 + 2] Cycloaddition of Allene-ynes to Form Non-racemic Spirooxindoles Beilstein Journal of Organic Chemistry. 2011 | Pubmed ID: 21647261 Allene Chemistry Beilstein Journal of Organic Chemistry. 2011 | Pubmed ID: 21512594 Chemical Methodology As a Source of Small-molecule Checkpoint Inhibitors and Heat Shock Protein 70 (Hsp70) Modulators Proceedings of the National Academy of Sciences of the United States of America. Apr, 2011 | Pubmed ID: 21502524 Diverging DOS Strategy Using an Allene-containing Tryptophan Scaffold and a Library Design That Maximizes Biologically Relevant Chemical Space While Minimizing the Number of Compounds ACS Combinatorial Science. Mar, 2011 | Pubmed ID: 21332123 Differentiating Mechanistic Possibilities for the Thermal, Intramolecular [2 + 2] Cycloaddition of Allene-ynes Journal of the American Chemical Society. Sep, 2010 | Pubmed ID: 20687581 A Thermally-induced, Tandem [3,3]-sigmatropic Rearrangement/[2 + 2] Cycloaddition Approach to Carbocyclic Spirooxindoles Beilstein Journal of Organic Chemistry. 2010 | Pubmed ID: 20502602 (3R,7aS)-3-(TRICHLOROMETHYL)TETRAHYDROPYRROLO[1,2-C]OXAZOL-1(3H)-ONE: AN AIR AND MOISTURE STABLE REAGENT FOR THE SYNTHESIS OF OPTICALLY ACTIVE α-BRANCHED PROLINES Organic Syntheses; an Annual Publication of Satisfactory Methods for the Preparation of Organic Chemicals. Jan, 2009 | Pubmed ID: 21331348 PHOSPHINE-CATALYZED [4+2] ANNULATION: SYNTHESIS OF ETHYL 6-PHENYL-1-TOSYL-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLATE Organic Syntheses; an Annual Publication of Satisfactory Methods for the Preparation of Organic Chemicals. Mar, 2009 | Pubmed ID: 20161208 Synthesis of the Naturally Occurring (-)-1,3,5-Tri-O-Caffeoylquinic Acid Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. Feb, 2009 | Pubmed ID: 20157344 Rh(I)-catalyzed Cyclocarbonylation of Allenol Esters to Prepare Acetoxy 4-alkylidenecyclopent-3-en-2-ones The Journal of Organic Chemistry. Nov, 2009 | Pubmed ID: 19821580 Cdc25B Dual-specificity Phosphatase Inhibitors Identified in a High-throughput Screen of the NIH Compound Library Assay and Drug Development Technologies. Jun, 2009 | Pubmed ID: 19530895 Design and Synthesis of a Library of Tetracyclic Hydroazulenoisoindoles Journal of Combinatorial Chemistry. May-Jun, 2009 | Pubmed ID: 19366169 Toward a Molecular Understanding of the Interaction of Dual Specificity Phosphatases with Substrates: Insights from Structure-based Modeling and High Throughput Screening Current Medicinal Chemistry. 2008 | Pubmed ID: 18855677 A General Synthetic Route to Differentially Functionalized Angularly and Linearly Fused [6-7-5] Ring Systems: a Rh(I)-catalyzed Cyclocarbonylation Reaction The Journal of Organic Chemistry. Jul, 2008 | Pubmed ID: 18522429 Diverging Rh(I)-catalyzed Carbocylization Strategy to Prepare a Library of Unique Cyclic Ethers Journal of Combinatorial Chemistry. Mar-Apr, 2008 | Pubmed ID: 18271514 Mo(CO)6- and [Rh(CO)2Cl]2-catalyzed Allenic Cyclocarbonylation Reactions of Alkynones: Efficient Access to Bicyclic Dienediones Organic Letters. Mar, 2008 | Pubmed ID: 18232695 Design and Synthesis of a 3,4-dehydroproline Amide Discovery Library Journal of Combinatorial Chemistry. Jul-Aug, 2007 | Pubmed ID: 17567173 Structurally Unique Inhibitors of Human Mitogen-activated Protein Kinase Phosphatase-1 Identified in a Pyrrole Carboxamide Library The Journal of Pharmacology and Experimental Therapeutics. Sep, 2007 | Pubmed ID: 17538006 Rhodium(I)-catalyzed Allenic Carbocyclization Reaction Affording Delta- and Epsilon-lactams Organic Letters. Jan, 2007 | Pubmed ID: 17217301 Solution-phase Synthesis of a Tricyclic Pyrrole-2-carboxamide Discovery Library Applying a Stetter-Paal-Knorr Reaction Sequence Journal of Combinatorial Chemistry. May-Jun, 2006 | Pubmed ID: 16677007 Microwave-assisted Intramolecular [2 + 2] Allenic Cycloaddition Reaction for the Rapid Assembly of Bicyclo[4.2.0]octa-1,6-dienes and Bicyclo[5.2.0]nona-1,7-dienes Organic Letters. Aug, 2005 | Pubmed ID: 16048320 Heterocyclic Alpha-alkylidene Cyclopentenones Obtained Via a Pauson-Khand Reaction of Amino Acid Derived Allenynes. A Scope and Limitation Study Directed Toward the Preparation of a Tricyclic Pyrrole Library The Journal of Organic Chemistry. Mar, 2005 | Pubmed ID: 15730297 A Formal Total Synthesis of (-)-FR901483, Using a Tandem Cationic Aza-Cope Rearrangement/Mannich Cyclization Approach The Journal of Organic Chemistry. Feb, 2005 | Pubmed ID: 15675848 Allenes and Transition Metals: a Diverging Approach to Heterocycles Organic Letters. Jun, 2004 | Pubmed ID: 15200331 Rhodium(I)-catalyzed Ene-allene Carbocyclization Strategy for the Formation of Azepines and Oxepines Organic Letters. Jun, 2004 | Pubmed ID: 15200310 The First Total Synthesis of 15-deoxy-Delta12,14-prostaglandin J2 and the Unambiguous Assignment of the C14 Stereochemistry Organic Letters. Jan, 2004 | Pubmed ID: 14723515 Unique Strategy for the Assembly of the Carbon Skeleton of Guanacastepene A Using an Allenic Pauson-Khand-type Reaction Organic Letters. Sep, 2003 | Pubmed ID: 12967307 A Rhodium(I)-catalyzed Formal Allenic Alder Ene Reaction for the Rapid and Stereoselective Assembly of Cross-conjugated Trienes Journal of the American Chemical Society. Dec, 2002 | Pubmed ID: 12487589 Chiral Nonracemic Alpha-alkylidene and Alpha-silylidene Cyclopentenones from Chiral Allenes Using an Intramolecular Allenic Pauson-Khand-type Cycloaddition The Journal of Organic Chemistry. Jul, 2002 | Pubmed ID: 12126400 An Allenic Pauson-Khand-type Reaction: a Reversal in Pi-bond Selectivity and the Formation of Seven-membered Rings Organic Letters. May, 2002 | Pubmed ID: 12027650 Solid-Phase Synthesis of BRL 49653 The Journal of Organic Chemistry. Mar, 1999 | Pubmed ID: 11674245 Strategy for the Preparation of Allenes from Alpha,beta-Unsaturated and Saturated Ketones Via Enol Phosphates The Journal of Organic Chemistry. Sep, 1996 | Pubmed ID: 11667439 Microwave-assisted Intramolecular Dehydrogenative Diels-Alder Reactions for the Synthesis of Functionalized Naphthalenes/Solvatochromic Dyes Laura S. Kocsis1, Erica Benedetti1, Kay M. Brummond1 1Department of Chemistry, University of Pittsburgh JoVE 50511 Chemistry
Microwave-assisted Intramolecular Dehydrogenative Diels-Alder Reactions for the Synthesis of Functionalized Naphthalenes/Solvatochromic Dyes Laura S. Kocsis1, Erica Benedetti1, Kay M. Brummond1 1Department of Chemistry, University of Pittsburgh JoVE 50511 Chemistry